N ‐Heteroarylation of Sulfonamides: An Overview

N ‐Heteroaryl sulfonamides are an extremely significant variety of organosulfur compounds that are present in many significant FDA‐approved drugs and therapeutic agents. Therefore, synthesis of these N ‐heteroaryl sulfonamides is one of the most interesting topics among the synthetic organic chemist...

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Bibliographic Details
Published inAdvanced synthesis & catalysis Vol. 365; no. 18; pp. 3020 - 3043
Main Authors Ghosh, Sumit, Pal, Prajna Paramita, Hajra, Alakananda
Format Journal Article
LanguageEnglish
Published Heidelberg Wiley Subscription Services, Inc 19.09.2023
Subjects
Genotoxicity
Organosulfur compounds
Pharmacology
Sulfonamides
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Summary:N ‐Heteroaryl sulfonamides are an extremely significant variety of organosulfur compounds that are present in many significant FDA‐approved drugs and therapeutic agents. Therefore, synthesis of these N ‐heteroaryl sulfonamides is one of the most interesting topics among the synthetic organic chemists. Among the various synthetic methodologies, direct C−N bond formation through N ‐heteroarylation of sulfonamides has emerged as a procedure continued of choice as it bypasses the genotoxicity common in the traditional methods. This review encompasses and summarizes the progress and development in this subject with literature coverage up to June 2023.
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ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.202300545