A Rare Case of Laryngeal Osteosarcoma Causing Diagnostic Challenges

Laryngeal osteosarcomas are extremely rare. They cause diagnostic difficulty for the otolaryngologist and pathologist. Differentiation from sarcomatoid carcinoma is challenging but important, as clinical features and treatment strategies are different. Total laryngectomy is generally the preferred s...

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Published inCurēus (Palo Alto, CA) Vol. 15; no. 4; p. e37393
Main Authors Kumbul, Yusuf Ç, Akın, Vural, Yasan, Hasan, Özdoğan Yılmaz, Gizem, Ayyıldız, Veysel A
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 10.04.2023
Cureus
Subjects
Alcohol
Biopsy
Bone cancer
Cartilage
Case reports
Chemotherapy
Chronic obstructive pulmonary disease
Cytokeratin
Dyspnea
Endoscopy
Fibrosarcoma
General anesthesia
Hyperthyroidism
Larynx
Lymphatic system
Medical diagnosis
Metastasis
Otolaryngology
Pagets disease
Pathology
Radiation therapy
Radiology
Risk factors
Sarcoma
Smoking
Thyroid gland
histopathological examination
laryngeal osteosarcomas
sarcomatoid carcinomas
diagnostic challenges
total laryngectomy
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Summary:Laryngeal osteosarcomas are extremely rare. They cause diagnostic difficulty for the otolaryngologist and pathologist. Differentiation from sarcomatoid carcinoma is challenging but important, as clinical features and treatment strategies are different. Total laryngectomy is generally the preferred surgical approach for laryngeal osteosarcomas. Since lymph node metastasis is not expected, neck dissection is not needed. In this report, we present a case diagnosed with laryngeal osteosarcoma post the examination of the total laryngectomy specimen of a laryngeal tumor that could not be histopathologically differentiated by punch biopsy.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.37393