A Linear Formulation of Asynchronous Boolean Networks

A new linear approach is proposed to model the dynamics of asynchronous Boolean networks (ABNs). The continuous-time discrete-state model definition makes the ABN a suitable formulation to describe gene regulatory networks. The semi-tensor product of matrices is used as the algebraic tool for the li...

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Bibliographic Details
Published inIEEE control systems letters Vol. 3; no. 2; pp. 284 - 289
Main Authors Das, Haimabati, Deshpande, Anuj, Layek, Ritwik Kumar
Format Journal Article
LanguageEnglish
Published IEEE 01.04.2019
Subjects
Biological system modeling
Boolean functions
Computational modeling
Computational systems biology
Delays
Mathematical model
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Summary:A new linear approach is proposed to model the dynamics of asynchronous Boolean networks (ABNs). The continuous-time discrete-state model definition makes the ABN a suitable formulation to describe gene regulatory networks. The semi-tensor product of matrices is used as the algebraic tool for the linear formulation. The results on the dynamics of the ABN are elaborated with synthetic and biological examples.
ISSN:2475-1456
2475-1456
DOI:10.1109/LCSYS.2018.2869045