A case of mimicking angioedema： chin silicone granulomatous reaction spreading all over the face after receiving liquid silicone injection forty years previously

Liquid injectable silicone has been used for soft tissue augmentation for five decades. Many complications following liquid silicone injection have been reported. To diagnose and manage silicone granuloma remains difficult. Silicone granuloma must be diagnosed with the history of liquid silicone inj...

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Bibliographic Details
Published inChinese medical journal Vol. 124; no. 11; pp. 1747 - 1750
Main Authors Chen, Yu-Cheng, Chen, Mei-Ling, Chiu, Ying-Ming
Format Journal Article
LanguageEnglish
Published China Division of Endocrinology and Metabolism, Department of Internal Medicine Changhua Christian Hospital, Changhua, Taiwan, China%Department of Pathology, Changhua Christian Hospital, Changhua, Taiwan, China%Division of Rheurnatology, Department of Internal Medicine Changhua Christian Hospital, Changhua, Taiwan, China 05.06.2011
Subjects
Aged
Angioedema - diagnosis
Chin - pathology
Cosmetic Techniques - adverse effects
Female
Granuloma - diagnosis
Humans
Injections, Subcutaneous
Silicones - adverse effects
反应
水肿
注射
液体
硅胶
神经
肉芽肿
血管
methylprednisolone
angioedema
silicone granuloma
liquid silicone
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Summary:Liquid injectable silicone has been used for soft tissue augmentation for five decades. Many complications following liquid silicone injection have been reported. To diagnose and manage silicone granuloma remains difficult. Silicone granuloma must be diagnosed with the history of liquid silicone injection and the histology of tissue biopsy. We presented a case of granulomatous reaction after the injection of liquid silicone for chin augmentation forty years ago, causing total facial swelling, which mimicking angioedema initially. We administered methylprednisolone to the patient. Initial response to methylprednisolone was favorable.
Bibliography:Liquid injectable silicone has been used for soft tissue augmentation for five decades. Many complications following liquid silicone injection have been reported. To diagnose and manage silicone granuloma remains difficult. Silicone granuloma must be diagnosed with the history of liquid silicone injection and the histology of tissue biopsy. We presented a case of granulomatous reaction after the injection of liquid silicone for chin augmentation forty years ago, causing total facial swelling, which mimicking angioedema initially. We administered methylprednisolone to the patient. Initial response to methylprednisolone was favorable.
silicone granuloma; methylprednisolone; angioedema; liquid silicone
Yu-cheng Chen, Mei-ling Chen,Ying-ming Chiu Division of Endocrinology and Metabolism, Department of Internal Medicine, Department of Pathology, Division of Rheumatology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, China
11-2154/R
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0366-6999
2542-5641
2542-5641
DOI:10.3760/cma.j.issn.0366-6999.2011.11.027