Quaternary ammonium salts as highly efficient and green alkylating agents for N-alkylation of azaheterocycles under microwave irradiation

An efficient, simple and green procedure for N -alkylation of azaheterocycles by quaternary ammonium salts in the presence of K 2 CO 3 under microwave irradiation is described. Using this method, N -alkyl derivatives of azaheterocycles are obtained in good to excellent yields and short reaction time...

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Bibliographic Details
Published inJournal of the Iranian Chemical Society Vol. 5; no. Suppl 1; pp. S40 - S46
Main Authors Khalafi-Nezhad, A., Zare, A., Parhami, A., Hasaninejad, A., Moosavi Zare, A. R.
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2008
Subjects
Analytical Chemistry
Biochemistry
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Organic Chemistry
Physical Chemistry
Microwave
Quaternary ammonium salt
Green chemistry
Azaheterocycle
Alkylation
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Summary:An efficient, simple and green procedure for N -alkylation of azaheterocycles by quaternary ammonium salts in the presence of K 2 CO 3 under microwave irradiation is described. Using this method, N -alkyl derivatives of azaheterocycles are obtained in good to excellent yields and short reaction times.
ISSN:1735-207X
1735-2428
DOI:10.1007/BF03246487