Complex Antiplatelet Therapy Management in Patients Requiring Urgent Interventions for Pseudoachalasia and Esophageal Obstruction

This case report describes the use of intravenous (IV) cangrelor as a transient tool for antiplatelet bridging therapy in a 70-year-old male with coronary artery disease and esophageal strictures who underwent recent percutaneous coronary intervention (PCI) and subsequently required a pre-oral endos...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 16; no. 3; p. e57209
Main Authors Vallejo, Charles, Bvute, Kushinga, Hernandez, Oscar L
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 29.03.2024
Cureus
Subjects
Cardiology
Cardiovascular disease
Endoscopy
Esophagus
Gastroenterology
Internal Medicine
Oral administration
Patients
Stents
Surgery
Thrombosis
gastroenterology and endoscopy
cangrelor
antiplatelet therapy
plavix
primary percutaneous coronary intervention (pci)
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Summary:This case report describes the use of intravenous (IV) cangrelor as a transient tool for antiplatelet bridging therapy in a 70-year-old male with coronary artery disease and esophageal strictures who underwent recent percutaneous coronary intervention (PCI) and subsequently required a pre-oral endoscopic myomectomy (POEM) procedure. The patient was switched from oral clopidogrel to IV cangrelor drip prior to the procedure, which was successful in preventing stent thrombosis. The case highlights the potential benefits of IV antiplatelet therapy in patients unable to tolerate oral medications in the setting of esophageal obstructions following recent coronary stent placement in a critical care setting.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.57209