Evaluation of Trabecular Microarchitecture of Normal Osteoporotic and Osteopenic Human Vertebrae

Osteoporosis is defined by the National Institutes of Health as a skeletal disorder characterized by compromised bone strength, increasing fracture risk. Samples of vertebral cancellous bone were extracted from human cadavers from the T12 region. The comparative pre-selection of bone into the three...

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Bibliographic Details
Published inProcedia engineering Vol. 59; pp. 6 - 15
Main Authors Cesar, R., Boffa, R.S., Fachine, L.T., Leivas, T.P., Silva, A.M.H., Pereira, C.A.M., Reiff, R.B.M., Rollo, J.M.D.A.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 2013
Subjects
Calcaneal ultrasonometry
Cancellous bone
Microarchitecture
Microscopy
Microtomography
Osteoporosis
Vertebrae
X-ray diffraction
Osteoporosis
Vertebrae
Microarchitecture
Microscopy
X-ray diffraction
Calcaneal ultrasonometry
Microtomography
Cancellous bone
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Summary:Osteoporosis is defined by the National Institutes of Health as a skeletal disorder characterized by compromised bone strength, increasing fracture risk. Samples of vertebral cancellous bone were extracted from human cadavers from the T12 region. The comparative pre-selection of bone into the three groups was performed using the calcaneal ultrasonometry and evaluated by image analysis: microtomography, X-ray diffraction, optical microscopy e scanning electron microscopy. The results showed, for the diseased bone, degradation, reduction in the histomorfometric parameters and lower X-ray intensity. It is concluded that this characteristics indicates a validation in the assessment of fracture risk.
ISSN:1877-7058
1877-7058
DOI:10.1016/j.proeng.2013.05.087