Direct Asymmetric Michael Additions of Ketones to Nitroolefins and Chalcones Catalyzed by a Chiral C2-Symmetric Pyrrolidine-based Tetraamine

C2-Symmetric pyrrolidine-based tetraamine, available from commercially starting materials, showed good cata- lytic activity for asymmetric Michael additions of ketones to nitroalkenes especially to chalcones. The reactions proceeded to give the corresponding products in good yields and in a highly s...

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Published inChinese journal of chemistry Vol. 30; no. 11; pp. 2707 - 2713
Main Author 马世俊 吴璐璐 刘明 王永梅
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 01.11.2012
WILEY‐VCH Verlag
Wiley
Wiley Subscription Services, Inc
Subjects
asymmetric catalysis
C2对称
chalcones
Chemistry
Chemistry, Multidisciplinary
enantioselectivity
Ketones
Michael addition
Physical Sciences
Pyrrolidine
Science & Technology
tetraamine
不对称Michael加成反应
催化活性
吡咯烷
手性
查尔酮
硝基烯
胺
Michael addition
chalcones
enantioselectivity
BETA-NITROSTYRENES
ORGANOCATALYST
tetraamine
COMPLEXES
CARBONYL-COMPOUNDS
ALDEHYDES
asymmetric catalysis
NITRO-MICHAEL
NITROALKANES
PROLINE
CONJUGATE ADDITION
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Summary:C2-Symmetric pyrrolidine-based tetraamine, available from commercially starting materials, showed good cata- lytic activity for asymmetric Michael additions of ketones to nitroalkenes especially to chalcones. The reactions proceeded to give the corresponding products in good yields and in a highly selective manner.
Bibliography:31-1547/O6
C2-Symmetric pyrrolidine-based tetraamine, available from commercially starting materials, showed good cata- lytic activity for asymmetric Michael additions of ketones to nitroalkenes especially to chalcones. The reactions proceeded to give the corresponding products in good yields and in a highly selective manner.
asymmetric catalysis, Michael addition, tetraamine, chalcones, enantioselectivity
Ma, Shijun Wu, Lulu Liu, Ming Wang, Yongmei Department of Chemistry, The Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
ark:/67375/WNG-4X62D6WB-W
istex:9E249E850270F2F01D3CBC6AC0D186A397F80B8E
the Nankai University State Key Laboratory of Elemento-Organic Chemistry
National Basic Research Program of China (973 Program) - No. 2010CB833300
ArticleID:CJOC201200214
the Ph.D. Programs Foundation of Ministry of Education of China - No. 20090031110019
ObjectType-Article-1
SourceType-Scholarly Journals-1
content type line 14
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201200214