Synthesis of novel 2-aryl-3-benzoyl-1H-benzo[f]indole-4,9-diones using a domino reaction

[Display omitted] •One-pot multicomponent synthesis of 2-aryl-3-benzoyl-1H-benzo[f]indole-4,9-quinones.•A mechanism for the transformation has been proposed.•Single crystal X-ray structure of 2-phenyl-3-(4-fluorobenzoyl)-1H-benzo[f]indole-4,9-dione is provided. A convenient one-pot multicomponent sy...

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Published inTetrahedron letters Vol. 57; no. 39; pp. 4352 - 4355
Main Authors Nguyen, Trung Quang, Le Nhat, Thuy Giang, Vu Ngoc, Doan, Dang Thi, Tuyet Anh, Nguyen, Ha Thanh, Hoang Thi, Phuong, Nguyen, Hung Huy, Cao, Hai Thuong, Abbaspour Tehrani, Kourosch, Nguyen, Tuyen Van
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 28.09.2016
Subjects
2-Amino-1,4-naphthoquinone
Benzo[f]indole-4,9-dione
Domino reactions
Benzo[f]indole-4,9-dione
2-Amino-1,4-naphthoquinone
Domino reactions
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Summary:[Display omitted] •One-pot multicomponent synthesis of 2-aryl-3-benzoyl-1H-benzo[f]indole-4,9-quinones.•A mechanism for the transformation has been proposed.•Single crystal X-ray structure of 2-phenyl-3-(4-fluorobenzoyl)-1H-benzo[f]indole-4,9-dione is provided. A convenient one-pot multicomponent synthetic approach was developed for the synthesis of novel 2-aryl-3-benzoyl-1H-benzo[f]indole-4,9-diones using 2-amino-1,4-naphthoquinone, N-acylmethylpyridinium bromides, and a variety of aromatic aldehydes.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2016.08.042