Solvent interactions in the allylation of piperidine

The reaction between allylbromide and piperidine has been studied in different protic and aprotic solvents. The reaction is first order with respect to [allylbromide] and [piperidine]. A correlation analysis of the rate data with solvent properties shows that polarity (Y), polarizability (P), and el...

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Bibliographic Details
Published inInternational journal of chemical kinetics Vol. 41; no. 6; pp. 421 - 425
Main Authors Devender, T., Manikyamba, P.
Format Journal Article
LanguageEnglish
Published Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2009
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Summary:The reaction between allylbromide and piperidine has been studied in different protic and aprotic solvents. The reaction is first order with respect to [allylbromide] and [piperidine]. A correlation analysis of the rate data with solvent properties shows that polarity (Y), polarizability (P), and electrophilicity (E) of the solvent simultaneously influence the rate of reaction. From the regression analysis, information regarding the relative solvation of the reactants and the activated complex is obtained and a solvation model is proposed. © 2009 Wiley Periodicals, Inc. Int J Chem Kinet 41: 421–425, 2009
Bibliography:ark:/67375/WNG-VPK7QZBF-C
ArticleID:KIN20410
istex:1E1432541E261E603B9A5B6956526C571F25F745
ISSN:0538-8066
1097-4601
DOI:10.1002/kin.20410