Asymmetric microbial conversion of ( E)-2-benzylideneindan-1-one by the filamentous fungi Botrytis cinerea, Trichoderma viride, and Eutypa lata

The transformation of ( E)-2-benzylideneindan-1-one 1 by the filamentous fungi Botrytis cinerea, Trichoderma viride, and Eutypa lata as biocatalysts was studied. The results showed the catalytic potential of these fungi in affording several hydroxylation and reduction products, three of them reporte...

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Published inTetrahedron: asymmetry Vol. 22; no. 16; pp. 1653 - 1657
Main Authors Pinedo-Rivilla, Cristina, Aleu, Josefina, Collado, Isidro G.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 15.09.2011
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Summary:The transformation of ( E)-2-benzylideneindan-1-one 1 by the filamentous fungi Botrytis cinerea, Trichoderma viride, and Eutypa lata as biocatalysts was studied. The results showed the catalytic potential of these fungi in affording several hydroxylation and reduction products, three of them reported here for the first time. The absolute configuration of enantiomerically pure 2-benzylindane derivatives was determined.
ISSN:0957-4166
1362-511X
DOI:10.1016/j.tetasy.2011.09.010