A Pediatric Case of Ketosis-Prone Type 2 Diabetes Requiring Insulin Therapy

In recent years, cases of diabetic ketoacidosis (DKA) or ketosis as the initial manifestation of diabetes with a similar clinical course to that of type 2 diabetes have been reported. This phenotype has been recognized as ketosis-prone type 2 diabetes (KPD). Most cases of KPD occur in adults, and th...

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Published inCurēus (Palo Alto, CA) Vol. 14; no. 3; p. e23305
Main Authors Matsuura, Misa, Sugawara, Daisuke, Ichihashi, Ko
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 18.03.2022
Cureus
Subjects
Antibodies
Antigens
Case reports
Diabetes
Diabetic ketoacidosis
Endocrinology/Diabetes/Metabolism
Glucagon
Glucose
Haplotypes
Hemoglobin
Insulin
Insulin resistance
Ketosis
Laboratories
Patients
Pediatrics
Peptides
Potassium
Weight control
diabetic ketoacidosis (dka)
pediatric diabetes
insulin treatment
pediatric weight management
ketosis-prone diabetes
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Summary:In recent years, cases of diabetic ketoacidosis (DKA) or ketosis as the initial manifestation of diabetes with a similar clinical course to that of type 2 diabetes have been reported. This phenotype has been recognized as ketosis-prone type 2 diabetes (KPD). Most cases of KPD occur in adults, and the typical clinical course is that patients are often able to wean off insulin therapy after initial treatment. We report a pediatric case of ketosis-prone type 2 diabetes requiring insulin therapy with four years of follow-up. Our case suggests that patients with KPD may require strict management, including weight control, compared with patients with typical type 2 diabetes.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.23305