A Resected Case of Duodenal Neuroendocrine Carcinoma

We report a case of neuroendocrine carcinoma of the duodenum. A 76-year-old man came to our hospital, complaining of dizziness. Laboratory data showed anemia. Abdominal CT revealed a 3-cm mass on the ventral side of the pancreatic head, and duodenoscopy showed a 4-cm elevated lesion with ulceration...

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Published inNippon Shokaki Geka Gakkai zasshi Vol. 40; no. 4; pp. 405 - 409
Main Authors Fujisaki, Shigeru, Takashina, Motoi, Tomita, Ryouichi, Takayama, Tadatoshi, Oinuma, Toshimiti
Format Journal Article
LanguageJapanese
Published The Japanese Society of Gastroenterological Surgery 2007
Subjects
duodenum
neuroendocrine carcinoma
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Summary:We report a case of neuroendocrine carcinoma of the duodenum. A 76-year-old man came to our hospital, complaining of dizziness. Laboratory data showed anemia. Abdominal CT revealed a 3-cm mass on the ventral side of the pancreatic head, and duodenoscopy showed a 4-cm elevated lesion with ulceration in the first part of the duodenum. Biopsy showed a malignant epithelial neoplasm of the duodenum. Partial duodenectomy and excision of a metastatic lymph node was performed for a preoperative diagnosis of a duodenal cancer with a metastatic lymph node, and followed by adjuvant chemotherapy with tegafur. Immunohistochemical analysis showed positive staining for chromogranin and synaptophysin. The definitive diagnosis was neuroendocrine carcinoma of the duodenum. The patient has survived for more than 36 months after surgery with no signs of recurrence.
ISSN:0386-9768
1348-9372
DOI:10.5833/jjgs.40.405