Rhino-Orbital Cerebral Mucormycosis in a Non-diabetic Patient Following COVID-19 Infection: A Case Report and Literature Review

Rhino-orbital cerebral mucormycosis has been commonly seen during the coronavirus disease 2019 (COVID-19) pandemic. Several factors responsible for etiology and pathophysiology have been identified, among which corticosteroids and diabetes have contributed to the lion's share of the outbreak of...

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Published inCurēus (Palo Alto, CA) Vol. 14; no. 12; p. e32884
Main Authors Niazi, Maha, Vittorino, Isabella, Thwe, Hla, Alam, Benish, Awosika, Ayoola O, Omole, Adekunle E
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 23.12.2022
Cureus
Subjects
Abscesses
Antifungal agents
Blood vessels
Case reports
Cellulitis
COVID-19
Debridement
Diabetes
Disease
Edema
Fungal infections
Fungi
Hematology
Hemoglobin
HIV
Human immunodeficiency virus
Internal Medicine
Laboratories
Magnetic resonance imaging
Medicine
Mortality
Neurology
Patients
Sinuses
Steroids
Thrombosis
Ohio
Pakistan
United States > US
Karachi Pakistan
coronavirus disease 2019 (covid-19)
diabetes mellitus
rhino-orbito-cerebral mucormycosis
rhino-cerebral mucormycosis
mucormycosis
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Summary:Rhino-orbital cerebral mucormycosis has been commonly seen during the coronavirus disease 2019 (COVID-19) pandemic. Several factors responsible for etiology and pathophysiology have been identified, among which corticosteroids and diabetes have contributed to the lion's share of the outbreak of mucormycosis. In this report, we discuss a case of a 41-year-old non-diabetic male with a recent convalescence from COVID-19 infection presented with gradual vision loss and loss of sensations in his right eye. He was found to have periorbital swelling, restriction of extraocular movements in all gazes, chemosis, ptosis of the right eye, and right maxillary sinus tenderness. His serum investigations, radiologic findings, and blood culture were indicative of rhino-orbital cerebral mucormycosis. He was started on systemic liposomal amphotericin B immediately and underwent aggressive surgical debridement. A high index of clinical suspicion, aggressive multifaceted management, and follow-up are needed to have successful outcomes, thereby lowering the morbidity of coronavirus-associated mucormycosis.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.32884