Human Adenovirus Penton Base and Encapsidation Sequences Detected in Pelodiscus sinensis By Next Generation Sequencing

The Chinese soft-shelled turtle (Pelodiscus sinensis) has become one of the leading cultured organisms in China and South East Asia. The objectives of the present study were to use next generation sequencing to identify viral genomes present in liver tissues from Chinese soft-shelled turtle in China...

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Published inFuture virology Vol. 14; no. 7; pp. 453 - 460
Main Authors Xu, Cheng, Xu, Jiehao, Liu, Jiating, Chen, Yu, Evensen, Øystein, Munang’andu, Hetron Mweemba, Qian, Guoying
Format Journal Article
LanguageEnglish
Published London Future Medicine Ltd 01.07.2019
Subjects
Adenoviruses
Aquaculture
Contamination
Deoxyribonucleic acid
Disease
DNA
DNA polymerase
Encapsidation
Feces
Freshwater environments
Genomes
Homology
Infections
Liver
Next-generation sequencing
Pelodiscus sinensis
Phylogenetics
Reptiles & amphibians
Taxonomy
Turtles
Viruses
United States > US
China
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Summary:The Chinese soft-shelled turtle (Pelodiscus sinensis) has become one of the leading cultured organisms in China and South East Asia. The objectives of the present study were to use next generation sequencing to identify viral genomes present in liver tissues from Chinese soft-shelled turtle in China. BLAST analysis of viral sequences from liver samples showed high homology with the human adenovirus (HAdV) penton base and encapsidation proteins. This homology points to possible existence of HAdV in freshwater environments used for the culture of soft-shelled turtles. Therefore, our findings merit further investigations to determine possible contamination of HAdV in aquaculture environments and the possible role of the Chinese soft-shelled turtle in transmitting HAdV to humans.
ISSN:1746-0794
1746-0808
DOI:10.2217/fvl-2019-0056