A Rare Case Report of Osteosarcoma of Maxilla with Double Free-Flap Reconstruction

• Published in: Indian journal of surgical oncology Vol. 15; no. Suppl 1; pp. 172 - 178
• Main Authors: Dabas, Surendra K., Menon, Nandini N., Ranjan, Reetesh, Shukla, Himanshu, Gurung, Bikas, Tiwari, Sukirti, Chaddha, Yash, Sinha, Ajit, Kapoor, Rahul, Verma, Vinay Kumar, Arora, Saurabh, Sharma, Ashwani, Singh, Jasbir, Singal, Rishu, Mohan, Sandeep Kumar, Sachan, Seema
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01.03.2024
• Subjects: Case Report; Medicine; Medicine & Public Health; Oncology; Surgery; Surgical Oncology; Case report; Osteosarcoma; Bone tumour; Microvascular surgery; Free flap; Maxillary neoplasm; Sun ray appearance
• ISSN: 0975-7651; 0976-6952
• DOI: 10.1007/s13193-023-01846-1

Osteosarcomas are rare and highly malignant bone tumours which are composed of malignant mesenchymal cells producing osteoid or immature bone. Maxillary osteosarcomas are rare tumours accounting for less than 1% of head and neck malignancies. Aggressive surgical resection is the main modality of treatment with good reconstruction. Due to the complex anatomy and location of maxilla as well as its proximity to the skull, resection with negative margins is always a challenge and so is the reconstruction so as to reduce the morbidity of the patient and to also give a good functional and cosmetic outcome. Clinical outcomes can be improved with administration of neoadjuvant or adjuvant chemotherapy in selected cases and radiotherapy in case of positive margins. A 41-year-old male patient presented to the outpatient department with complaints of a bulge over the hard palate for the past 1 year. CT scan showed a 6 × 5 × 4 cm osseous expansile lesion arising from the maxillary bone. Biopsy of the tumour showed features of conventional high-grade osteosarcoma. Plate-preserving maxillectomy with tracheostomy was done followed by reconstruction with a double free flap. On post-operative day 1, the flap showed signs of venous congestion and a new free anterolateral thigh flap was done. Patient was discharged on day 7 with a Ryles tube and a tracheostomy tube in situ. Final histopathological examination showed that the tumour was a high-grade chondroblastic osteosarcoma. After regular post-operative visits in the outpatient department and evaluation with flexible laryngoscopy, patient was started on oral feed by day 10 and decannulated by day 15. He has been on regular follow-up for the past 1 year and shows no signs of recurrence or residual disease on clinical examination as well as imaging. Maxillary osteosarcoma is a rare bone tumour which requires accurate imaging and biopsy for accurate surgical planning. The ideal treatment modality is radical resection with negative margins and appropriate reconstruction. With the advent of microvascular surgery, free flaps form the backbone for reconstruction of such large defects.