Use of Iloprost for treatment of skin ischaemia after subcutaneous mastectomy and simultaneous prosthetic reconstruction

We report the case of a woman who underwent subcutaneous mastectomy and simultaneous prosthetic reconstruction for malignant disease. Following the procedure, the upper skin flap became progressively ischaemic. A continuous infusion of Iloprost, a prostacyclin analogue, (Schering Health Care Ltd) ap...

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Bibliographic Details
Published inBreast (Edinburgh) Vol. 2; no. 4; pp. 257 - 258
Main Authors Wilson, Y.G., Cawthorn, S.J.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.12.1993
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Summary:We report the case of a woman who underwent subcutaneous mastectomy and simultaneous prosthetic reconstruction for malignant disease. Following the procedure, the upper skin flap became progressively ischaemic. A continuous infusion of Iloprost, a prostacyclin analogue, (Schering Health Care Ltd) appeared to salvage the flap. We discuss the possible mechanisms for this action. To our knowledge, this is the first published case in which Iloprost has been used in this way.
ISSN:0960-9776
1532-3080
DOI:10.1016/0960-9776(93)90013-6