Homonymous Hemianopia: A Rare Presentation of Secondary Central Nervous System Neurolymphomatosis

Neurolymphomatosis is an atypical complication of non-Hodgkin lymphoma and leukaemia involving infiltration of neurotropic neoplastic cells in the central or peripheral nervous system. A 28-year-old Malay lady with background diffuse large B-cell lymphoma stage IV presented with left homonymous hemi...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 10; no. 5; p. e2708
Main Authors Awis Qarni, Fadil, Tai, Evelyn, Wh, Wan-Hazabbah, Husin, Azlan
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 29.05.2018
Cureus
Subjects
Case reports
Chemotherapy
Edema
Lymphoma
Medical imaging
Metastasis
Nervous system
NMR
Nuclear magnetic resonance
Oncology
Ophthalmology
Patients
Radiology
diffuse large b-cell lymphoma
neurolymphomatosis
non-hodgkin lymphoma
lymphoma
homonymous hemianopia
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Summary:Neurolymphomatosis is an atypical complication of non-Hodgkin lymphoma and leukaemia involving infiltration of neurotropic neoplastic cells in the central or peripheral nervous system. A 28-year-old Malay lady with background diffuse large B-cell lymphoma stage IV presented with left homonymous hemianopia associated with cognitive function deterioration. Her best corrected visual acuity was 6/9 in both eyes. Magnetic resonance imaging (MRI) of the brain showed a lesion suggestive of secondary lymphomatous infiltration of the splenium of corpus callosum. The patient underwent chemotherapy, after which repeated MRI showed a reduction in the lesion size. Homonymous hemianopia is a rare presentation of secondary central nervous system neurolymphomatosis. A comprehensive history, physical examination, and radiological imaging are essential to establish the diagnosis in patients presenting with visual field defects.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.2708