Exploiting novel process windows for the synthesis of meso-substituted porphyrins under continuous flow conditions

Porphyrin synthesis by classical methods frequently involves the use of high temperatures, toxic and dangerous reagents yielding the product in very low amounts and with poor scalability. Herein, we have studied the synthesis of meso -substituted porphyrins under continuous flow conditions, thus dem...

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Bibliographic Details
Published inRSC advances Vol. 5; no. 102; pp. 84350 - 84355
Main Authors Momo, Patrícia B., Bellete, Barbara S., Brocksom, Timothy J., de Souza, Rodrigo O. M. A., de Oliveira, Kleber T.
Format Journal Article
LanguageEnglish
Published 2015
Subjects
Continuous flow
Dangerous
Porphyrins
Synthesis
Toxic
Toxicology
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Summary:Porphyrin synthesis by classical methods frequently involves the use of high temperatures, toxic and dangerous reagents yielding the product in very low amounts and with poor scalability. Herein, we have studied the synthesis of meso -substituted porphyrins under continuous flow conditions, thus demonstrating scale-up for the porphyrin synthesis in a safe, cost-competitive, highly pure, reproducible and robust manner.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:2046-2069
2046-2069
DOI:10.1039/C5RA16962C