Some validation aspects on the analytical method for assaying carcinogenic amines from textile dyes
Chemicals safety control and ecological properties have become a priority for the textile industry in order to avoid the negative effects on humans and environment. The increasing interest for toxicology of textiles is determined by the presence of dangerous compounds in clothes generated from dyein...
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Published in | Industria textilă (Bucharest, Romania : 1994) Vol. 69; no. 3; pp. 249 - 256 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Bucharest
The National Research & Development Institute for Textiles and Leather - INCDTP
01.01.2018
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Subjects | |
Online Access | Get full text |
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Summary: | Chemicals safety control and ecological properties have become a priority for the textile industry in order to avoid the
negative effects on humans and environment. The increasing interest for toxicology of textiles is determined by the
presence of dangerous compounds in clothes generated from dyeing and finishing processes. In order to protect human
health, European Regulations as Oeko Tex Standard 100 and REACH Regulation limit the presence of dangerous
chemicals, such as aromatic amines, generated by reductive cleavage of azo dyes, by no more than 30 mg/kg of textile
material. The main goal of this research work was to develop and validate a HPLC/MWD method for precise and reliable
identification and quantification of carcinogenic aromatic amines derived from banned azo dye specific to the textile
industry. The simultaneous determination of 24 regulated aromatic amines has been conducted by two chromatographic
methods according to SR EN ISO 14362-1:2017 in order to avoid matrix interferences and compounds misidentification
due to the presence of structural isomers. Preliminary analyses to establish the maximum absorption wavelength of
each standard solution of aromatic amine were performed simultaneously at four wavelengths, 240, 280, 305 and
380 nm. With the scope of demonstrating the consistency, reliability and accuracy of the analysed data, both liquid and
gas chromatographic method were validated. Parameters as selectivity, precision, limit of detection and limit of
quantification of the analytical methods were evaluated. The certainty of the determinations was also proved by the
results of proficiency testing conducted by IIS Netherlands on azo dyes in textiles. |
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ISSN: | 1222-5347 |
DOI: | 10.35530/IT.069.03.1521 |