Diagnostics of thyroid cancer: Limitations of the existing methods and perspectives for future developments

A novel approach to the development of a precise method of intraoperative diagnostics of thyroid cancer has been proposed on the basis of fundamental study of proteasomes in malignant tumors of mammals and human. The method is based on estimation of proteasome activity in small fragments of the tumo...

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Bibliographic Details
Published inBiology bulletin of the Russian Academy of Sciences Vol. 41; no. 4; pp. 318 - 323
Main Authors Sharova, N. P, Sumedi, I. R, Astakhova, T. M, Plekhanova, A. S, Lyupina, Y. V, Shashova, E. E, Kondakova, I. V, Rodoman, G. V
Format Journal Article
LanguageEnglish
Published Moscow Springer-Verlag 2014
Pleiades Publishing
Subjects
Biochemistry
Biomedical and Life Sciences
Cell Biology
diagnostic techniques
Ecology
humans
Life Sciences
proteasome endopeptidase complex
thyroid neoplasms
Zoology
Papillary Thyroid Carcinoma
Fine Needle Aspiration Biopsy
Thyroid Nodule
Thyroid Cancer
Biology Bulletin
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Summary:A novel approach to the development of a precise method of intraoperative diagnostics of thyroid cancer has been proposed on the basis of fundamental study of proteasomes in malignant tumors of mammals and human. The method is based on estimation of proteasome activity in small fragments of the tumor and adjacent tissues.
Bibliography:http://dx.doi.org/10.1134/S1062359014040104
ISSN:1062-3590
1608-3059
DOI:10.1134/S1062359014040104