Thermoresponsive fluorinated polyacrylamides with low cytotoxicity

We report the unique thermoresponsive properties of fluorinated polyacrylamides, poly[N-(2,2-difluoroethyl)acrylamide] (P2F). The solubility of fluorinated polyacrylamides in water can be easily controlled by changing the number of fluorine atoms in N-ethyl groups. Moreover, we demonstrate that fluo...

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Published inPolymer chemistry Vol. 4; no. 7; pp. 2219 - 2223
Main Authors Bak, Jae Min, Kim, Kyung-Bin, Lee, Ji-Eun, Park, Yongjin, Yoon, Sang Sun, Jeong, Han Mo, Lee, Hyung-il
Format Journal Article
LanguageEnglish
Published 01.01.2013
Subjects
Atomic properties
Fluorination
Fluorine
Polyacrylamides
Polymer chemistry
Solubility
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Summary:We report the unique thermoresponsive properties of fluorinated polyacrylamides, poly[N-(2,2-difluoroethyl)acrylamide] (P2F). The solubility of fluorinated polyacrylamides in water can be easily controlled by changing the number of fluorine atoms in N-ethyl groups. Moreover, we demonstrate that fluorinated polyacrylamides are less cytotoxic than poly(N-isopropylacrylamide) (PNIPAM).
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ISSN:1759-9954
1759-9962
DOI:10.1039/C2PY20747H