Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide ( PTA ), with high sensitivity and selectivity for the detection of uric acid ( UA ) was developed and first time imaging of uric acid in living cells in water was achieved. 1 H NMR and density functional studies on the system have...

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Published inRSC advances Vol. 6; no. 71; pp. 66774 - 66778
Main Authors Sahoo, Prithidipa, Sarkar, Himadri Sekhar, Das, Sujoy, Maiti, Kalipada, Uddin, Md Raihan, Mandal, Sukhendu
Format Journal Article
LanguageEnglish
Published 01.01.2016
Subjects
Cells (biology)
Density
Derivatives
Fluorescence
Imaging
Pyrenes
Thymine
Uric acid
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Summary:A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide ( PTA ), with high sensitivity and selectivity for the detection of uric acid ( UA ) was developed and first time imaging of uric acid in living cells in water was achieved. 1 H NMR and density functional studies on the system have been carried out to determine the nature of the interaction between probe PTA and UA .
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ISSN:2046-2069
2046-2069
DOI:10.1039/C6RA15980J