Synergy Analysis of Back Muscle Activities in Patients With Adolescent Idiopathic Scoliosis Based on High-Density Electromyogram

• Published in: IEEE transactions on biomedical engineering Vol. 69; no. 6; pp. 2006 - 2017
• Main Authors: Wang, Wei, Jiang, Naifu, Teng, Lijun, Sui, Minghong, Li, ChunZhen, Wang, Lin, Li, Guanglin
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.06.2022; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Adolescent idiopathic scoliosis; Adolescents; Artificial intelligence; Back; Bending; Density; Electrodes; Electromyography; high-density electromyography; Matrix decomposition; Muscle contraction; muscle synergy; Muscles; Muscular function; Neuromuscular; Neuromuscular system; Patients; Rotation; Scoliosis; Spine; spine motions; Statistical analysis; Topographic mapping
• ISSN: 0018-9294; 1558-2531
• DOI: 10.1109/TBME.2021.3133583

Objective: Adolescent idiopathic scoliosis (AIS) is a common structural spinal deformity and is typically associated with altered muscle properties. However, it is still unclear how muscle activities and the underlying neuromuscular control are changed in the entire scoliotic zone, restricting the corresponding pathology investigation and treatment enhancements. Methods: High-density electromyogram (HD-EMG) was utilized to explore the neuromuscular synergy of back muscle activities. For each of ten AIS patients and ten healthy subjects for comparison, an HD-EMG array was placed on their back from T8 to L4 to record EMG signals when performing five spinal motions (flexion/extension, lateral bending, axial rotation, siting, and standing). From the HD-EMG recordings, muscle synergies were extracted using the non-negative matrix factorization method and the topographical maps of EMG root-mean-square were constructed. Results: For both the AIS and healthy subjects, the experimental results indicated that two muscle synergy groups could explain over 90% of recorded muscle activities for all five motions. During flexion/extension, the patients presented statistically significant higher activations on the convex side in the entire root-mean-square maps and synergy vector maps ( p < 0.05). During lateral bending and axial rotation, the patients exhibited less activated muscles on the dominant actuating side relative to the contralateral side and their synergy vector maps showed a less homogenous and more diffuse distribution of muscle contraction with statistically different centers of gravity. Conclusion: The findings suggest a scoliotic spine might adopt an altered modular muscular coordination strategy to actuate different dominant muscles as adapted compensations for the deformation.