Phentermine Use During First and Second Trimesters Associated with Fetal Stroke

Phentermine is a sympathomimetic amine used for the short-term weight loss that has been associated with ischemic and hemorrhagic strokes in adults. The effects of this medication on a developing fetus are not well studied. We present the case of a woman who was taking phentermine during the first t...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 11; no. 11; p. e6170
Main Authors D'Adesky, Nathan, Ghosh, Suman
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 16.11.2019
Cureus
Subjects
Anatomy
Appetite
Cardiovascular disease
Case reports
Cerebral palsy
Cesarean section
Cysts
Diabetes
Family medical history
Neurology
NMR
Nuclear magnetic resonance
Pediatrics
Pregnancy
Pulmonary hypertension
Stroke
Urine
Veins & arteries
United States > US
in-utero
weight loss medications
pregnancy
phentermine
weight loss
porencephaly
fetal
stroke
fetus
sympathomimetic
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Summary:Phentermine is a sympathomimetic amine used for the short-term weight loss that has been associated with ischemic and hemorrhagic strokes in adults. The effects of this medication on a developing fetus are not well studied. We present the case of a woman who was taking phentermine during the first two trimesters of pregnancy and subsequently delivered a child with bilateral porencephalic cysts likely due to a prenatal stroke.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.6170