Amniotic membrane transplantation for ocular surface burns

• Published in: Revista Brasileira de Oftalmologia Vol. 83
• Main Authors: Dias, Paula Basso, Ghem, Mariela Regina Dalmarco, Martinelli, Ana Caroline, Linhares, Anna Carolina Badotti, Wasilewski, Daniel
• Format: Journal Article
• Language: English
• Published: Sociedade Brasileira de Oftalmologia 2024
• Subjects: Amnion/transplantation; Anterior eye segment; Chemical burns; Eye burns; Membranes/transplantation
• ISSN: 0034-7280; 1982-8551
• DOI: 10.37039/1982.8551.20240012

ABSTRACT Objective: To analyze the morphological and functional long-term outcomes of amniotic membrane transplantation after ocular surface chemical burns. Methods: This prospective study analyzed 7 patients who suffered from severe ocular surface burn and underwent amniotic membrane transplantation from 2015 to 2020 in Hospital de Clínicas - Universidade Federal do Paraná. Results: Out of the seven patients, six (85.7%) suffered unilateral burn and one (14.3%) suffered bilateral burn. Five of them had alkali burns (71.4%), one had acid burn (14.3%) and one suffered gunpowder fireworks burn (14.3%). Mean age was 29.4 years (±standard deviation 13.3, range 14.0 to 47.0 years). Mean visual acuity at first presentation was 1.83±0.79 logMAR (0.015 decimal) and mean VA after a follow-up of 1 year was 0.85±0.70 logMAR (0.141 decimal). The visual acuity significantly improved from 1.83±0.79 to 0.85±0.70 logMAR (p<0.05). Conclusion: Amniotic membrane transplantation is an effective adjunctive treatment in the management of ocular surface chemical burns with potential to improve the final vision outcome.