Iodine-Containing Coating with Prolonged Antimicrobial Activity Based on Water-Insoluble Polymer Matrix

UV spectroscopy demonstrated formation of a complex of iodine with vinylpyrrolidone and butyl methacrylate in nonpolar ethanol medium. This complex is soluble in alcohol and insoluble in water. Application of an alcohol solution of the complex to a wound surface results in formation of a water-imper...

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Bibliographic Details
Published inBiomedical engineering Vol. 46; no. 6; pp. 237 - 240
Main Authors Davydov, A. B., Belyh, S. I., Kravets, V. V.
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.03.2013
Springer Nature B.V
Subjects
Antimicrobial activity
Antimicrobial agents
Biomaterials
Biomedical engineering
Biomedical Engineering and Bioengineering
Coating
Coatings
Engineering
Ethanol
Iodine
Polymer coatings
Polymer matrix composites
Polymers
Spectroscopy
Spectrum analysis
Vinylpyrrolidone
Wound healing
Vapor Permeable Water
Antimicrobial Effect
Iodine Concentration
Wound Surface
Iodine
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Summary:UV spectroscopy demonstrated formation of a complex of iodine with vinylpyrrolidone and butyl methacrylate in nonpolar ethanol medium. This complex is soluble in alcohol and insoluble in water. Application of an alcohol solution of the complex to a wound surface results in formation of a water-impermeable film with antimicrobial properties facilitating wound healing. The antimicrobial coating lasts for 1–3 days. Use of the Iodpolycom iodine polymer coating makes it possible to abandon gauze bandages. It also reduces suppurative complications from 34 to 5% relative to control. The Iodpolycom complex is commercially available.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0006-3398
1573-8256
DOI:10.1007/s10527-013-9314-0