α2-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat

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Bibliographic Details
Published inEuropean journal of pharmacology Vol. 613; no. 1-3; pp. 64 - 67
Main Authors ROMERO, Thiago R. L, DUARTE, Igor D. G
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier 01.06.2009
Subjects
Biological and medical sciences
Medical sciences
Pharmacology. Drug treatments
α2-Adrenergic receptor
Agonist
Rat
Rodentia
Xylazine
3',5'-GMP
Adrenoceptor
Analgesia
α
Vertebrata
Mammalia
Analgesic
Arginine
Aminoacid
Animal
Nitric oxide
Cyclic GMP
α-Adrenergic receptor agonist
Peripheral antinociception
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ISSN:0014-2999
1879-0712
DOI:10.1016/j.ejphar.2009.04.031