Memantine in the treatment and prophylaxis of bipolar II disorder and comorbid fibromyalgia: a case report

We have recently reported that memantine has a clinically relevant antimanic and long-lasting mood-stabilizing effect in treatment-resistant bipolar disorders, both as augmenting agent and as monotherapy. We have also observed an acute antimanic and sustained mood-stabilizing effect in a small numbe...

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Bibliographic Details
Published inJournal of psychiatric practice Vol. 20; no. 3; p. 232
Main Authors Serra, Giulia, DE Chiara, Lavinia, Koukopoulos, Alexia Emilia, Koukopoulos, Athanasios, Serra, Gino, Kahn, David A
Format Journal Article
LanguageEnglish
Published United States 01.05.2014
Subjects
Bipolar Disorder - complications
Bipolar Disorder - drug therapy
Bipolar Disorder - physiopathology
Diagnostic and Statistical Manual of Mental Disorders
Dopamine Agents - administration & dosage
Female
Fibromyalgia - complications
Fibromyalgia - drug therapy
Fibromyalgia - psychology
Humans
Memantine - administration & dosage
Middle Aged
Pain Management - methods
Psychiatric Status Rating Scales
Symptom Assessment - methods
Treatment Outcome
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Summary:We have recently reported that memantine has a clinically relevant antimanic and long-lasting mood-stabilizing effect in treatment-resistant bipolar disorders, both as augmenting agent and as monotherapy. We have also observed an acute antimanic and sustained mood-stabilizing effect in a small number of patients with bipolar I disorder who had had minimal previous pharmacotherapy. In this article, we report the case of a young woman suffering from bipolar II disorder with associated fibromyalgia, in whom memantine showed an acute antimanic and a long-term prophylactic effect on both bipolar disorder as well as the associated fibromyalgia syndrome.
ISSN:1538-1145
DOI:10.1097/01.pra.0000450324.44661.12