Preparation of 2 ',3 '-oxirane-fused carbocyclic nucleosides based on N-substituted 2-azabicyclo[2.2.1]-hept-5-en-3-ones

The epoxidation of N-substituted 2-azabicyclo[2.2.1]hept-5-en-3-ones (1) led to the exo-selective formation of epoxides (2), and the use of 2 for the preparation of 2',3'-oxirane-fused carbocyclic nucleosides (10) was attempted.

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Bibliographic Details
Published inHeterocycles Vol. 64; pp. 241 - 248
Main Authors Ishikura, M, Matsumoto, K, Murakami, A
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 31.12.2004
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:The epoxidation of N-substituted 2-azabicyclo[2.2.1]hept-5-en-3-ones (1) led to the exo-selective formation of epoxides (2), and the use of 2 for the preparation of 2',3'-oxirane-fused carbocyclic nucleosides (10) was attempted.
ISSN:0385-5414
1881-0942
DOI:10.3987/COM-04-S(P)19