Diagnosis and treatment challenges in a rare Clostridium infection: A case report

The genus includes >180 species of Gram-positive, anaerobic, sporulating bacteria. Under certain conditions, these can cause a wide range of invasive infections in humans. occurs in the commensal intestinal flora and related bacteremia typically occurs secondary to an injury to the intestinal muc...

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Published inBiomedical reports Vol. 21; no. 5; p. 149
Main Authors Bălaș-Maftei, Bianca, Florea, Carmen-Elena, Obreja, Maria, Rotaru, Alexandra, Miftode, Larisa, Miftode, Egidia, Irimie-Băluță, Erika-Raluca, Manciuc, Carmen
Format Journal Article
LanguageEnglish
Published England Spandidos Publications UK Ltd 01.11.2024
D.A. Spandidos
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Summary:The genus includes >180 species of Gram-positive, anaerobic, sporulating bacteria. Under certain conditions, these can cause a wide range of invasive infections in humans. occurs in the commensal intestinal flora and related bacteremia typically occurs secondary to an injury to the intestinal mucosa and in the presence of predisposing conditions, such as gastrointestinal disorders, malignancies, diabetes, HIV infection or neutropenia. The current study presents the case of a 70-year-old male patient, a rural resident living in poverty, with a history of alchohol consumption and cardiovascular pathology. Several initial and subsequent diagnoses were ruled out by successive investigations (e.g., stroke, meningitis, localized tetanus). Blood cultures were eventually found positive for and the patient developed septic shock despite treatment with metronidazole and penicillin G. Once switched to carbapenem, the patient progressed favorably, suggesting that carbapenem could work as a first-line antibiotic treatment for infections.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:2049-9434
2049-9442
2049-9442
DOI:10.3892/br.2024.1837