Evaluation of dynamic magnetic resonance imaging during arteriography using gadopentetate dimeglumine for the detection of hepatocellular carcinoma

• Published in: Kanzo Vol. 34; no. 9; pp. 705 - 709
• Main Authors: FUJITA, Takeshi, CHOJI, Takashi, ITO, Katsuyoshi, NAKANISHI, Takashi
• Format: Journal Article
• Language: Japanese
• Published: The Japan Society of Hepatology 1993
• Subjects: Dynamic MRI; Gd-DTPA
• ISSN: 0451-4203; 1881-3593
• DOI: 10.2957/kanzo.34.705

Dynamic magnetic resonance (MR) imaging during arteriography using Gd-DTPA was performed to evaluate its clinical usefulness in 12 patients with 14 hepatocellular carcinoma confirmed by CT, angiography, and high serum AFP level or fine-needle biopsy. After conventional hepatic arteriography, the patients were transferred to the MR unit and MR imaging during arteriography was obtained with the gradient-echo technique synchronously starting manual injection of Gd-DTPA diluted with normal sahne via the hepatic artery using 5-F Cobra angiographic catheter. The scan time was 240r 26 seconds and 40 or 6 slice-section images of the arterial phase were acquired during a single breath-hold. The tumors showed iso or low signal intensity on the precontrast images, but were revealed a high signal intensity area relative to surrounding normal parenchyma during the arterial phase and a clear liver-to-lesion contrast was acquired. Especially in two cases which had been treated, the local recurrence was not detected on the conventional angiographic examinations but was visualized as a high signal intensity area on MR imaging during arteriography. In addition to in another two cases, fan-shaped enhancement was seen by the tumor suggesting the presence of an arterio-portal shunt. This new technique seemed to be useful for regional detection of hepatocellular carcinomas obtaining in the optional plane and for accurate estimating the local recurrence and an arterio-portal shunt.