Microwave induced synthesis of thieno[2,3-b]quinoline-2-carboxylic acids and alkyl esters and their antibacterial activity

A series of thieno[2,3-b]quinoline-2-carboxylic acids and alkyl esters, (3a-i) have been synthesized by the condensation of 2-chloro-3-formyl quinolines (1a-c) with thioglycolic acid/alkyl esters under microwave irradiation using anhydrous potassium carbonate. These compounds were characterized by e...

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Bibliographic Details
Published inJournal of sulfur chemistry Vol. 27; no. 4; pp. 347 - 351
Main Authors Raghavendra, M., Bhojya Naik, Halehatty S., Sherigara, Bailure S.
Format Journal Article
LanguageEnglish
Published Taylor & Francis 01.08.2006
Subjects
Alkyl derivatives
Microwave irradiation
Thienoquinolines
Thioglycolic acid
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Summary:A series of thieno[2,3-b]quinoline-2-carboxylic acids and alkyl esters, (3a-i) have been synthesized by the condensation of 2-chloro-3-formyl quinolines (1a-c) with thioglycolic acid/alkyl esters under microwave irradiation using anhydrous potassium carbonate. These compounds were characterized by elemental analysis, IR, 1 H NMR, and mass spectral studies. Their antibacterial activity was also evaluated.
ISSN:1741-5993
1741-6000
DOI:10.1080/17415990600825611