Synthesis, Structure, Antimicrobial, and Hepatotoxic Behavior of 28-and 32-Membered Bearing Tetra Amide Functions and Their Tin(II) Complexes

Tin(II) complexes of 1,8-diaminooctane and dicarboxylic acids (succinic acid and adipic acid) have been synthesized and studied. These complexes have been characterized by chemical analysis and IR, 1 H NMR, 13 C NMR, and 119 Sn NMR spectral studies, as well as X-ray powder diffraction, molecular wei...

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Published inPhosphorus, sulfur, and silicon and the related elements Vol. 182; no. 2; pp. 475 - 483
Main Authors Chauhan, Shikha, Chaudhary, Ashu, Singh, R. V.
Format Journal Article
LanguageEnglish
Published Taylor & Francis Group 01.01.2007
Subjects
biologically potent ligands
Biomedical applications
bivalent tin(II) complexes
hepatotoxic behavior
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ISSN1042-6507
1563-5325
DOI10.1080/10426500600977312

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Summary:Tin(II) complexes of 1,8-diaminooctane and dicarboxylic acids (succinic acid and adipic acid) have been synthesized and studied. These complexes have been characterized by chemical analysis and IR, 1 H NMR, 13 C NMR, and 119 Sn NMR spectral studies, as well as X-ray powder diffraction, molecular weight determinations, and conductivity measurements. An octahedral geometry around the tin atom is suggested for [Sn(MacL n )Cl 2 ] complexes. The pathogenicity of certain microbial infections associated with the complexes made it obligatory to distinguish between a parent counter part and their tin(II) complexes. To make the subject interesting, biomedical applications of the complexes have been discussed.
ISSN:1042-6507
1563-5325
DOI:10.1080/10426500600977312