Stability analysis of multi-group deterministic and stochastic epidemic models with vaccination rate

We discuss in this paper a deterministic multi-group MSIR epidemic model with a vaccination rate, the basic reproduction number Ro, a key parameter in epidemiology, is a threshold which determines the persistence or extinction of the disease. By using Lyapunov function techniques, we show if Ro is g...

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Published inChinese physics B Vol. 23; no. 9; pp. 19 - 34
Main Author 王志刚 高瑞梅 樊晓明 韩七星
Format Journal Article
LanguageEnglish
Published 01.09.2014
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ISSN1674-1056
2058-3834
1741-4199
DOI10.1088/1674-1056/23/9/090201

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Summary:We discuss in this paper a deterministic multi-group MSIR epidemic model with a vaccination rate, the basic reproduction number Ro, a key parameter in epidemiology, is a threshold which determines the persistence or extinction of the disease. By using Lyapunov function techniques, we show if Ro is greater than 1 and the deterministic model obeys some conditions, then the disease will prevail, the infective persists and the endemic state is asymptotically stable in a feasible region. If Ro is less than or equal to 1, then the infective disappear so the disease dies out. In addition, stochastic noises around the endemic equilibrium will be added to the deterministic MSIR model in order that the deterministic model is extended to a system of stochastic ordinary differential equations. In the stochastic version, we carry out a detailed analysis on the asymptotic behavior of the stochastic model. In addition, regarding the value of Ro, when the stochastic system obeys some conditions and Ro is greater than 1, we deduce the stochastic system is stochastically asymptotically stable. Finally, the deterministic and stochastic model dynamics are illustrated through computer simulations.
Bibliography:We discuss in this paper a deterministic multi-group MSIR epidemic model with a vaccination rate, the basic reproduction number Ro, a key parameter in epidemiology, is a threshold which determines the persistence or extinction of the disease. By using Lyapunov function techniques, we show if Ro is greater than 1 and the deterministic model obeys some conditions, then the disease will prevail, the infective persists and the endemic state is asymptotically stable in a feasible region. If Ro is less than or equal to 1, then the infective disappear so the disease dies out. In addition, stochastic noises around the endemic equilibrium will be added to the deterministic MSIR model in order that the deterministic model is extended to a system of stochastic ordinary differential equations. In the stochastic version, we carry out a detailed analysis on the asymptotic behavior of the stochastic model. In addition, regarding the value of Ro, when the stochastic system obeys some conditions and Ro is greater than 1, we deduce the stochastic system is stochastically asymptotically stable. Finally, the deterministic and stochastic model dynamics are illustrated through computer simulations.
MSIR epidemic model, equilibrium, graph theory, Brownian motion
11-5639/O4
Wang Zhi-Gang, Gao Rui-Mei, Fan Xiao-Ming , and Han Qi-Xing (1. College of Mathematics, Jilin University, Changchun 130012, China; 2. School of Mathematical Sciences, Harbin Normal University, Harbin 150500, China; 3. College of Science, Changchun University of Science and Technology, Changchun 130022, China; 4. School of Mathematics, Changchun Normal University, Changchun 130032, China)
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ISSN:1674-1056
2058-3834
1741-4199
DOI:10.1088/1674-1056/23/9/090201