Pembrolizumab Therapy Leading to Complete Remission for Recurrence of Pulmonary Metastases after their Resection and Radical Cystectomy following Gemcitabine and Cisplatin Therapy

A 64-year-old man was diagnosed with invasive bladder and right lower ureteral urothelial cancer with right pelvic lymph node and lung metastases. He received four courses of gemcitabine and cisplatin therapy. He underwent lung metastasectomy and radical cystoprostatectomy, with not only primary les...

Full description

Saved in:
Bibliographic Details
Published inCase reports in urology Vol. 2024; pp. 1 - 4
Main Authors Ishida, Kyohei, Hasegawa, Go, Hashimoto, Takehisa, Ikeda, Yohei, Hara, Noboru, Nishiyama, Tsutomu
Format Journal Article
LanguageEnglish
Published New York Hindawi 17.01.2024
Hindawi Limited
Subjects
Biomarkers
Bladder cancer
Cancer therapies
Case Report
Chemotherapy
Lung cancer
Lymphatic system
Medical prognosis
Metastasis
Oncology
Patients
Radiation therapy
Remission (Medicine)
Tumors
Urological surgery
Online AccessGet full text

Cover

More Information
Summary:A 64-year-old man was diagnosed with invasive bladder and right lower ureteral urothelial cancer with right pelvic lymph node and lung metastases. He received four courses of gemcitabine and cisplatin therapy. He underwent lung metastasectomy and radical cystoprostatectomy, with not only primary lesions but also metastatic lesions showing a complete response. New multiple lung metastases were revealed five months after adjuvant chemotherapy. On starting pembrolizumab therapy, the metastatic lesions are notably reduced in size. He is currently receiving pembrolizumab therapy, and no recurrence has been observed for over one year.
Bibliography:Academic Editor: Tun-Chieh Chen
ISSN:2090-696X
2090-6978
DOI:10.1155/2024/5586448