Hepatic Encephalopathy: From the Pathogenesis to the New Treatments
Hepatic encephalopathy is a frequent and serious complication of liver cirrhosis; the pathophysiology of this complication is not fully understood although great efforts have been made during the last years. There are few prospective studies on the epidemiology of this complication; however, it is k...
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Published in | ISRN Hepatology Vol. 2014; pp. 236268 - 16 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
United States
Hindawi Publishing Corporation
04.06.2014
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Subjects | |
Online Access | Get full text |
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Summary: | Hepatic encephalopathy is a frequent and serious complication of liver cirrhosis; the pathophysiology of this complication is not fully understood although great efforts have been made during the last years. There are few prospective studies on the epidemiology of this complication; however, it is known that it confers with high short-term mortality. Hepatic encephalopathy has been classified into different groups depending on the degree of hepatic dysfunction, the presence of portal-systemic shunts, and the number of episodes. Due to the large clinical spectra of overt EH and the complexity of cirrhotic patients, it is very difficult to perform quality clinical trials for assessing the efficacy of the treatments proposed. The physiopathology, clinical manifestation, and the treatment of HE is a challenge because of the multiple factors that converge and coexist in an episode of overt HE. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 Academic Editors: L.-T. Huang, Y. Shimizu, and M.-H. Zheng |
ISSN: | 2314-4041 2314-4041 |
DOI: | 10.1155/2014/236268 |