Clinical Study of Adjuvant Arthritis Rats Monitored by Thermography

We investigated the thermogram of rat tails using an acute inflammatory model applied percutaneously to rats with adjuvant induced arthritis. After 2-4 weeks injection, the mean temperatures, as well as calories of the tails, were significantly higher in adjuvant treated groups than in the control g...

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Published inOrthopedics & Traumatology Vol. 47; no. 2; pp. 450 - 453
Main Authors Kanai, Shigeyuki, Susuki, Ryutaro, Okano, Hideyuki, Taniguchi, Norimasa
Format Journal Article
LanguageEnglish
Published West-Japanese Society of Orthopedics & Traumatology 1998
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ISSN0037-1033
1349-4333
DOI10.5035/nishiseisai.47.450

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Summary:We investigated the thermogram of rat tails using an acute inflammatory model applied percutaneously to rats with adjuvant induced arthritis. After 2-4 weeks injection, the mean temperatures, as well as calories of the tails, were significantly higher in adjuvant treated groups than in the control group. This increase of both parameters was correlated with the degree of edema. These results suggest that monitoring the temperature and calories of the tails in adjuvant arthritis rats could be a useful method for pre-clinically evaluating the efficacy of anti-inflammatory drugs.
ISSN:0037-1033
1349-4333
DOI:10.5035/nishiseisai.47.450