Clinical Study of Adjuvant Arthritis Rats Monitored by Thermography
We investigated the thermogram of rat tails using an acute inflammatory model applied percutaneously to rats with adjuvant induced arthritis. After 2-4 weeks injection, the mean temperatures, as well as calories of the tails, were significantly higher in adjuvant treated groups than in the control g...
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Published in | Orthopedics & Traumatology Vol. 47; no. 2; pp. 450 - 453 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
West-Japanese Society of Orthopedics & Traumatology
1998
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Subjects | |
Online Access | Get full text |
ISSN | 0037-1033 1349-4333 |
DOI | 10.5035/nishiseisai.47.450 |
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Summary: | We investigated the thermogram of rat tails using an acute inflammatory model applied percutaneously to rats with adjuvant induced arthritis. After 2-4 weeks injection, the mean temperatures, as well as calories of the tails, were significantly higher in adjuvant treated groups than in the control group. This increase of both parameters was correlated with the degree of edema. These results suggest that monitoring the temperature and calories of the tails in adjuvant arthritis rats could be a useful method for pre-clinically evaluating the efficacy of anti-inflammatory drugs. |
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ISSN: | 0037-1033 1349-4333 |
DOI: | 10.5035/nishiseisai.47.450 |