THE ROLE OF FIBRIN GLUE AND SUTURE ON THE FIXATION OF ULTRA FROZEN PRESERVED MENISCUS TRANSPLANTATION IN RABBITS

• Published in: Revista brasileira de ortopedia (English ed.) Vol. 44; no. 5; pp. 397 - 403
• Main Authors: Reckers, Leandro José, Fagundes, Djalma José, Pozo Raymundo, José Luiz, Granata Júnior, Geraldo Sérgio de Mello, Moreira, Márcia Bento, Paiva, Vanessa Carla, Negrini Fagundes, Anna Luiza, Cohen, Moises
• Format: Journal Article
• Language: English
• Published: Brazil Elsevier Editora Ltda 01.01.2009; Elsevier
• Subjects: Fibrin tissue adhesive; Meniscus; Original; Rabbits; Transplantation; Fibrin tissue adhesive; Rabbits; Transplantation; Meniscus
• ISSN: 2255-4971; 2255-4971
• DOI: 10.1016/S2255-4971(15)30269-X

Objective: To evaluate the ability of fibrin adhesive in promoting the meniscus fixation within two, four and eight weeks compared to the conventional soft-tissue suture technique. Materials and Methods: 36 right medial menisci of rabbits preserved at negative 73° Celsius for 30 days were transplanted to animals of the same sample and fixed with soft-tissue suture or fibrin glue. After 2, 4 or 8 weeks, the appearance of the menisci and the quality of fixation were macroscopically checked and evaluated by a scoring system. The findings were subjected to the statistical study of variance analysis (p ≤ 0.05%). Results: The deep-frozen meniscus preservation maintained the integrity of the meniscus transplant, and, macroscopically, there was no significant reduction of the length of the meniscus in all post-transplant periods (p = 0.015). The menisci fixed with fibrin showed slight changes in color and surface roughness. There were no signs of rejection or infection in both groups. Suture fixation scoring was superior (p = 0.015) in all periods (80% of total fixation) as compared to the setting promoted by fibrin (20% of total fixation). Conclusion: The homologous transplantation of the meniscus of rabbits experienced various degrees of integration to the knee according to the fixation method; the surgical soft tissues suturing technique was shown to be superior in the evaluation of scores compared to the fixation with fibrin adhesive.