Basal cell carcinoma: Epidemiology; pathophysiology; clinical and histological subtypes; and disease associations

As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical ed...

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Published inJournal of the American Academy of Dermatology Vol. 80; no. 2; p. 303
Main Authors Cameron, Michael C, Lee, Erica, Hibler, Brian P, Barker, Christopher A, Mori, Shoko, Cordova, Miguel, Nehal, Kishwer S, Rossi, Anthony M
Format Journal Article
LanguageEnglish
Published United States 01.02.2019
Subjects
Biopsy, Needle
Carcinogenesis - radiation effects
Carcinoma, Basal Cell - epidemiology
Carcinoma, Basal Cell - pathology
Carcinoma, Basal Cell - physiopathology
Carcinoma, Squamous Cell - epidemiology
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - physiopathology
Female
Humans
Immunohistochemistry
Incidence
Male
Prognosis
Risk Assessment
Skin Neoplasms - epidemiology
Skin Neoplasms - pathology
Skin Neoplasms - physiopathology
Ultraviolet Rays - adverse effects
associations
epidemiology
skin cancer
BCC
cost
genetics
nonmelanoma skin cancer
basal cell carcinoma
natural history
keratinocyte carcinoma
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Summary:As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical education article will provide a comprehensive and contemporary review of basal cell carcinoma. The first article in this series describes our current understanding of this disease regarding epidemiology, cost, clinical and histopathologic presentations, carcinogenesis, natural history, and disease associations.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
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ISSN:1097-6787
1097-6787
DOI:10.1016/j.jaad.2018.03.060