Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients

• Published in: Turkish journal of osteoporosis Vol. 20; no. 3; pp. 93 - 97
• Main Authors: Vural, Meltem, Topkarcı, Zeynep, Ersoy, Sedef, Erhan, Belgin, Gündüz, Berrin
• Format: Journal Article
• Language: English
• Published: Galenos Yayinevi 01.12.2014
• Subjects: 25-hydroxyvitamin D; Psoriasis; psoriasis area severity index
• ISSN: 2146-3816; 2147-2653
• DOI: 10.4274/tod.30502

Objective: To investigate the serum 25-hydroxy vitamin D levels in systemic treatment planned premenopausal psoriasis patients and compare it with the same age and sex matched healthy volunteers. Materials and Methods: Forty-one psoriasis patients and 57 healthy controls (total of 98) were included in the study. Serum 25-hydroxy vitamin D levels were compared between the two groups; also the relationship of disease activity and 25-hydroxy Vitamin D levels were examined in patients with psoriasis. Probability values of <0.05 were considered as statistically significant. Results: The mean age of patients with psoriasis and control groups were not statistically different (p>0.05). In addition, the mean 25-hydroxy vitamin D levels were not significantly different among the two groups (p>0.05). 25-hydroxy vitamin D levels were no significantly different in patients with and without psoriatic arthritis (p>0.05). No significant correlation was found between psoriasis area severity index PASI values, age or 25-hydroxy vitamin D levels (p>0.05). Conclusion: The low levels of vitamin D in population is reported to be common. In our study, similar low vitamin D levels were found in healthy volunteers and premenopausal psoriasis patients. Serum 25-hydroxy vitamin D levels were not correlated with disease activity in patients with psoriasis. Correlation between psoriasis, disease activity and vitamin D levels should be investigated in larger populations. (Turkish Journal of Osteoporosis 2014;20: 93-7)