Solitary plasmacytoma of bone and asymptomatic multiple myeloma

Most patients with multiple myeloma (MM) present with symptoms, have evidence of generalized disease, and require chemotherapy promptly to reduce the malignant clone. Some patients present with a local symptom from a single plasmacytoma but no myeloma elsewhere. Such patients usually become free of...

Full description

Saved in:
Bibliographic Details
Published inBlood Vol. 96; no. 6; pp. 2037 - 2044
Main Authors Dimopoulos, Meletios A., Moulopoulos, Lia A., Maniatis, Alice, Alexanian, Raymond
Format Journal Article
LanguageEnglish
Published 15.09.2000
Online AccessGet full text

Cover

More Information
Summary:Most patients with multiple myeloma (MM) present with symptoms, have evidence of generalized disease, and require chemotherapy promptly to reduce the malignant clone. Some patients present with a local symptom from a single plasmacytoma but no myeloma elsewhere. Such patients usually become free of symptoms after local radiotherapy. In patients with MM without symptoms, the diagnosis is made on the basis of screening laboratory tests. In patients with either solitary plasmacytoma of bone or asymptomatic MM, systemic treatment should be deferred until there is evidence of disease progression.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V96.6.2037.h8002037_2037_2044