Assessment of electrocardiographic parameters in healthy dogs undergoing dobutamine stress testing

The electrocardiographic effects of dobutamine stress testing (10 to 40 microg/kg/minute) were investigated in five conscious healthy dogs. We studied the changes in the duration and amplitude of P wave, PR interval, duration of QRS complex, R wave amplitude, QT interval, and heart rate. Development...

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Bibliographic Details
Published inSchweizer Archiv für Tierheilkunde Vol. 147; no. 12; p. 541
Main Authors Sousa, M G, Pereira-Neto, G B, Carareto, R, Gerardi, D G, Camacho, A A
Format Journal Article
LanguageEnglish
Published Switzerland 01.12.2005
Subjects
Animals
Cardiotonic Agents - adverse effects
Dobutamine - adverse effects
Dog Diseases - chemically induced
Dogs - physiology
Dose-Response Relationship, Drug
Electrocardiography - methods
Electrocardiography - veterinary
Exercise Test - methods
Exercise Test - veterinary
Female
Tachycardia, Ventricular - chemically induced
Tachycardia, Ventricular - veterinary
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Summary:The electrocardiographic effects of dobutamine stress testing (10 to 40 microg/kg/minute) were investigated in five conscious healthy dogs. We studied the changes in the duration and amplitude of P wave, PR interval, duration of QRS complex, R wave amplitude, QT interval, and heart rate. Development of arrhythmias and ST segment abnormalities were also recorded. It was observed that dobutamine significantly affects atrioventricular-nodal conduction and total electrical systole time at higher infusion rates. Only a single episode of sustained ventricular tachycardia was observed, which was promptly restored to sinus rhythm shortly after dobutamine infusion was discontinued. No ST segment abnormalities were detected. Dobutamine stress testing was concluded to play a role in some ECG parameters at higher infusion rates.
ISSN:0036-7281
DOI:10.1024/0036-7281.147.12.541