Characteristics of melanomacrophage centers in the liver and spleen of the roach Rutilus rutilus (Cypriniformes: Cyprinidae) in Lake Kotokel during the Haff disease outbreak

• Published in: Journal of ichthyology Vol. 54; no. 1; pp. 104 - 110
• Main Authors: Pronina, S. V, Batueva, M. D. -D, Pronin, N. M
• Format: Journal Article
• Language: English
• Published: Boston Springer-Verlag 2014; Springer US
• Subjects: Biomedical and Life Sciences; Cyprinidae; Cypriniformes; death; disease outbreaks; erythrocytes; fish; Freshwater; hemosiderin; lakes; Life Sciences; liver; parenchyma; pigments; Rutilus rutilus; spleen; Zoology; Lake Baikal; Russia, Siberia, Baykal L; melanomacrophage centers; hepatotoxin; roach; spleen; liver; histopathology; Haff disease; microcystin
• ISSN: 0032-9452; 1555-6425
• DOI: 10.1134/S003294521401010X

Characteristics of morphology and number of melanomacrophage centers (MMCs) in the liver and spleen of the roach Rutilus rutilus and the amount of pigments in MMCs during the Haff disease outbreak and the death of fish in Lake Kotokel in relation to these parameters in the roach from Lake Baikal are described. Pathological changes in the microvasculature and parenchyma in the liver of the roach from Lake Kotokel were found. The area of melanomacrophage centers in the liver of the roach from this lake was significantly smaller, whereas the number and size of these centers in the spleen was significantly larger than in the roaches from Lake Baikal. Among the pigments studied, the strongest response to the content of this toxin in the water body was shown by hemosiderin. An increase in its amount in the spleen MMCs testifies to an enhanced degradation of erythrocytes and iron release, which may be caused by the damage of cells of the erythrocyte lineage by the toxin.