Continuous three-dimensional radiation dosimetry in tissue-equivalent phantoms using electron paramagnetic resonance in L-alpha-alanine

A new tissue-equivalent phantom material has been developed which also acts as a dosimeter. The new phantom material has a similar elemental composition to that of soft tissue and has a density 1.1 g/cm3. The phantom has an agar-gel base, and contains crystallized L-alpha-alanine which traps radiati...

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Bibliographic Details
Published inMedical physics (Lancaster) Vol. 14; no. 4; p. 646
Main Authors Wielopolski, L, Maryanski, M, Ciesielski, B, Forman, A, Reinstein, L E, Meek, A G
Format Journal Article
LanguageEnglish
Published United States 01.07.1987
Subjects
Alanine
Electron Spin Resonance Spectroscopy - methods
Humans
Models, Anatomic
Muscles - anatomy & histology
Radiotherapy - methods
Radiotherapy Dosage
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Summary:A new tissue-equivalent phantom material has been developed which also acts as a dosimeter. The new phantom material has a similar elemental composition to that of soft tissue and has a density 1.1 g/cm3. The phantom has an agar-gel base, and contains crystallized L-alpha-alanine which traps radiation-induced free radicals. Samples from the phantom were analyzed by an electron paramagnetic resonance (EPR) spectrometer and the intensity of the EPR signal was related to the absorbed dose. When calibrated, the phantom material acts as a dosimeter, with applications in radiation therapy.
ISSN:0094-2405
DOI:10.1118/1.596033