Assessment of the value of 6-min walk test to predict the severity of interstitial lung disease among Indian patients
Introduction: The prevalence of interstitial lung disease (ILD) is increasing. High-resolution computerized tomography (HRCT), despite having limitations, remains the choice of method for diagnosis and assessment of severity of ILD. Objective: To determine the efficacy of 6-min walk test to assess t...
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Published in | Journal of Association of Chest Physicians Vol. 12; no. 1; pp. 11 - 19 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Medknow Publications and Media Pvt. Ltd
01.01.2024
Wolters Kluwer Medknow Publications |
Subjects | |
Online Access | Get full text |
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Summary: | Introduction: The prevalence of interstitial lung disease (ILD) is increasing. High-resolution computerized tomography (HRCT), despite having limitations, remains the choice of method for diagnosis and assessment of severity of ILD. Objective: To determine the efficacy of 6-min walk test to assess the severity of the ILD compared to HRCT. Methodology: A cross-sectional study was done among 40 patients with ILD in a tertiary hospital in Hyderabad. The data included age, gender, smoking, HRCT, 6-min walk test, spirometry, diffusion lung capacity and medical history. Mann–Whitney U test, Kruskal–Wallis test, and ROC curve were used to determine the outcomes. Results: The mean age of participants was 57.18 + 13.01 years. 62.5% never smoked. Overall, 50% had severe ILD, and the rest had mild to moderate. The distance walked per 6-min, SpO 2 before and SpO 2 after, was significantly lower ( p = 0.001; 0.002; <0.001, respectively) among patients with severe ILD than mild or moderate. The sensitivity and 1-specificity of the distance walked in 6-min to detect the severity of ILD was 0.90 and 0.31, respectively; sensitivity and 1-specificity of SpO 2 before the test was 0.81 and 0.34, while that of SpO 2 after the test was 0.90 and 0.17, respectively. Conclusion: This study found that the 6-min walk test is highly sensitive and specific for predicting the severity of ILD among patients. All three components of the 6-min walk test: distance, oxygen saturation before, and oxygen saturation after the test significantly lowered and were independent predictors of severe ILD. |
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ISSN: | 2320-8775 2320-9089 |
DOI: | 10.4103/jacp.jacp_54_23 |