Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism

Cardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponad...

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Published inCase reports in cardiology Vol. 2021; pp. 1 - 6
Main Authors Baghal, Moaaz, Amrutiya, Viralkumar, Patel, Bhoomi, Patel, Rutwik, Hernandez, Jonathan, Ahmed, Mohamed, Lo, Abraham, Gabelman, Mark
Format Journal Article
LanguageEnglish
Published New York Hindawi 10.11.2021
Hindawi Limited
Wiley
Subjects
Abdomen
Antigens
Ascites
Biopsy
Blood pressure
Case Report
Case reports
Chest tubes
Heart
Hypothyroidism
Pneumothorax
Proteins
Severe acute respiratory syndrome coronavirus 2
Thyroid cancer
Thyroidectomy
Ultrasonic imaging
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Summary:Cardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponade with the finding of elevation of a blood tumor marker, CA-125, in the setting of nonadherence to thyroid replacement therapy. She was managed by surgical pericardial window and abdominal paracentesis, with replacement of thyroid hormones leading to resolution of the tamponade and ascites. CA-125 elevation associated with cardiac tamponade and myxedema ascites due to hypothyroidism is very rare, and we aim to shed light on the importance of having a broad differential when approaching cardiac tamponade and understand the association between CA-125 and hypothyroidism.
Bibliography:Academic Editor: Assad Movahed
ISSN:2090-6404
2090-6412
DOI:10.1155/2021/2666601