Stabilization of papain and lysozyme for application to cosmetic products

For cosmetic applications, papain or lysozyme was conjugated to a soluble biopolymer produced by Schizophyllum commune. Stability of the conjugated enzymes were significantly enhanced, such that more than 90% of the initial activity remained after a month storage at 45 degree C, even in a cosmetic f...

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Bibliographic Details
Published inBiotechnology letters Vol. 22; no. 2; pp. 137 - 140
Main Authors SIM, Y.-C, LEE, S.-G, LEE, D.-C, KANG, B.-Y, PARK, K.-M, LEE, J.-Y, KIM, M.-S, CHANG, I.-S, RHEE, J.-S
Format Journal Article
LanguageEnglish
Published Dordrecht Springer 01.01.2000
Subjects
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
Industrial applications and implications. Economical aspects
Other applications
Schizophyllum commune
Cosmetic
Enzyme
Stabilization
Cysteine endopeptidases
Basidiomycetes
Papain
Fungi
Dextran
Ethylene oxide polymer
Glucan
Peptidases
Chemical modification
Schizophyllum commune
Ingredient
Glycosidases
Biopolymer
Hydrolases
Conjugation
O-Glycosidases
Lysozyme
Thallophyta
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Summary:For cosmetic applications, papain or lysozyme was conjugated to a soluble biopolymer produced by Schizophyllum commune. Stability of the conjugated enzymes were significantly enhanced, such that more than 90% of the initial activity remained after a month storage at 45 degree C, even in a cosmetic formulation including various oils and surfactants. Cosmetic lotion containing 1% papain conjugate was more effective in exfoliating stratum corneum of skin than the lotion containing 5% lactic acid, one of the popular exfoliating agents.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0141-5492
DOI:10.1023/A:1005670323912