A silver-functionalized metal–organic framework with effective antibacterial activity
Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-funct...
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| Published in | New journal of chemistry Vol. 46; no. 13; pp. 5922 - 5926 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Cambridge
Royal Society of Chemistry
28.03.2022
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-functional groups was constructed and postsynthetically modified with Ag(
i
) for antibacterial applications. The Ag@Zn-MOF exhibits high antibacterial activity toward
E. coli
and
S. aureus
, which reaches ∼100% bacterial reduction at a concentration as low as 25 μg
MOF
cm
−3
(corresponding to 1.7 μg
Ag
cm
−3
). These results demonstrated that Ag(
i
)-modified MOFs could act as effective antimicrobial agents with potential applications in food and healthcare. |
|---|---|
| AbstractList | Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-functional groups was constructed and postsynthetically modified with Ag(
i
) for antibacterial applications. The Ag@Zn-MOF exhibits high antibacterial activity toward
E. coli
and
S. aureus
, which reaches ∼100% bacterial reduction at a concentration as low as 25 μg
MOF
cm
−3
(corresponding to 1.7 μg
Ag
cm
−3
). These results demonstrated that Ag(
i
)-modified MOFs could act as effective antimicrobial agents with potential applications in food and healthcare. Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-functional groups was constructed and postsynthetically modified with Ag(i) for antibacterial applications. The Ag@Zn-MOF exhibits high antibacterial activity toward E. coli and S. aureus, which reaches ∼100% bacterial reduction at a concentration as low as 25 μgMOF cm−3 (corresponding to 1.7 μgAg cm−3). These results demonstrated that Ag(i)-modified MOFs could act as effective antimicrobial agents with potential applications in food and healthcare. |
| Author | Yuan, Shuai Li, Cheng-Hui Zhao, Pei-Chen Li, Zhe Wu, Ya-Meng Jia, Bin |
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| SubjectTerms | Antimicrobial agents E coli Functional groups Metal-organic frameworks Nanoparticles Silver |
| Title | A silver-functionalized metal–organic framework with effective antibacterial activity |
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