A silver-functionalized metal–organic framework with effective antibacterial activity

Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-funct...

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Published inNew journal of chemistry Vol. 46; no. 13; pp. 5922 - 5926
Main Authors Wu, Ya-Meng, Zhao, Pei-Chen, Jia, Bin, Li, Zhe, Yuan, Shuai, Li, Cheng-Hui
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 28.03.2022
Subjects
Antimicrobial agents
E coli
Functional groups
Metal-organic frameworks
Nanoparticles
Silver
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Summary:Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-functional groups was constructed and postsynthetically modified with Ag( i ) for antibacterial applications. The Ag@Zn-MOF exhibits high antibacterial activity toward E. coli and S. aureus , which reaches ∼100% bacterial reduction at a concentration as low as 25 μg MOF cm −3 (corresponding to 1.7 μg Ag cm −3 ). These results demonstrated that Ag( i )-modified MOFs could act as effective antimicrobial agents with potential applications in food and healthcare.
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ISSN:1144-0546
1369-9261
DOI:10.1039/D1NJ06183F